NIOSH Study Designates Bisphenol A as a Skin Sensitizer

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On April 12, 2011, the National Institute of Occupational Safety and Health (NIOSH) published a skin notation profile for Bisphenol A (BPA).  This profile found enough evidence to classify BPA as causing skin sensitization.  Sensitization is a specific immune-mediated response (responses mediated by the immune system, including allergic responses) that develops following exposure to a chemical, which, upon re-exposure, can lead to allergic contact dermatitis (ACD) or other immune-mediated diseases such as asthma, depending on the site and route of re-exposure.  BPA is a high-production-volume (HPV) chemical used in the manufacturing of epoxy resins, plastics, and flame retardants.  NIOSH evaluated several case reports and predictive animal studies that indicated BPA as being a skin sensitizer and can cause photoallergy.  Hence, NIOSH has assigned a SK:SEN notation (skin:sensitizer) for BPA.  With BPA used as a flame retardant avoiding coming into skin contact with it could be very difficult. 

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Study suggests that being too clean can make people sick

Image via WikipediaA recent study by the University of Michigan School of Public Health suggests that people who are overexposed to endocrine-disrupting compounds (EDCs) may suffer more allergies and negative effects to their immune systems.  Study suggests that being too clean can make people sick.  This study indicates that young people who are overexposed to antibacterial soaps containing triclosan may suffer more allergies, and exposure to higher levels of Bisphenol A (BPA) among adults may negatively influence the immune system.  Triclosan is a chemical compound widely used in products such as antibacterial soaps, toothpaste, pens, diaper bags and medical devices.  BPA is found in many plastics and, for example, as a protective lining in food cans.  Both of these chemicals are in a class of environmental toxicants called endocrine-disrupting compounds (EDCs), which are believed to negatively impact human health by mimicking or affecting hormones.  "We found that people over age 18 with higher levels of BPA exposure had higher CMV antibody levels, which suggests their cell-mediated immune system may not be functioning properly," said Erin Rees Clayton, research investigator at the U-M School of Public Health and first author on the paper.  The study also found that people age 18 and under with higher levels of triclosan were more likely to report diagnosis of allergies and hay fever.  There is growing concern among the scientific community and consumer groups that these EDCs are dangerous to humans at lower levels than previously thought.

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• Study suggests that being too clean can make people sick (eurekalert.org)
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• "Study: Bisphenol A, Triclosan and The Hygienic Hypothesis" and related posts (afludiary.blogspot.com)
• You can be too clean: Chemicals in soap can harm children's health (dailymail.co.uk)
• Study Shows That Pesticides Make Women Sick (food.change.org)

Future Environment Designs discussion "The Pollution Within"

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In 2006 we discussed in our blog Future Environment Designs: "The Pollution Within" from Plattsburgh, NY about an article we read in National Geographic about all the different chemicals we have inside our body.  Its interesting that on November 7, 2009 that the New York Times Op-Ed Columnist by Nicolas Kristof (http://www.nytimes.com/2009/11/08/opinion/08kristof.html) wrote "Chemicals in our Foods and Bodies".  Specifically discussing the issues with bisphenol A (BPA), its a synthetic estrogen used in plastics.  Some of you might even know that Suffolk County, New York has banned it.  BPA has been linked to a number of illnesses from breast cancer to obesity, from attention deficit disorder to genital abnormalities in boys and girls alike (not conclusively).  So all of this still begs the question when are we going to do complete research on the chemicals we use to determine whether by themselves or multiple chemicals together cause or can cause illnesses or cancers.

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